Defeat Green Goblin in the Prologue.
Defeat Doctor Octopus in Chapter 1.
Defeat The Hood in Chapter 2.
Defeat Elektra in Chapter 3.
Defeat The Kingpin in Chapter 4.
Defeat Juggernaut in Chapter 5.
Defeat Magneto in Chapter 6.
Defeat Mister Sinister in Chapter 7.
Defeat Doctor Doom in Chapter 8.
Complete Chapter 9 in Story Mode.
Find and Defeat a Cosmic Doop.
Visit Six Different Headquarters.
Defeat a Training Room Target Dummy.
Complete 14 Different Operations.
Rescue 100 civilians in Midtown Patrol.
Reach level 60 with any hero.
Explore all of the Treasure Rooms in each chapter of Story Missions.
Complete 50 Legendary Quests.
Apply a Modification to an Artifact.
Open 50 Bounty Chests in Operations.
Complete the Super Heroic Trial with any hero.
Level any vendor to level 10.
Fully upgrade a Legendary Item.
Collect any 100 Relics of the same type.
Defeat 150 Super Villains in Midtown Manhattan.
Defeat 7 Different Super Villains in their Showdowns.
Complete 24 different Alerts in Story missions.
Complete the Cosmic Trial with any hero.
Get Five Heroes to Level 60.
Defeat 10 different members of the Sinister Six.
Alone, defeat Shocker in under 50 seconds upon entering the Abandoned Subway Operation.
