True Shadow Mage Playing Aeon, finish the game by using Shadow Bolt to deal the killing blow on each of the guardians.
True Spirit Channeler Playing Mukai, finish the game by entering every card of every level (not counting extra cards or the shortcut card)
True Rogue Occultist Playing Rasimov, activate the Immortal ability 6 times and finish the game with full health.
Gear Up! In a single playthrough, upgrade 6 skills from each of the three skill trees, and equip a gold glyph.
Pew! Pew! Pew! In a single combat, generate 60 reflected projectiles by shooting at a reflective-aura protected creature.